From Wikipedia, the free encyclopedia Brian Regan is a stand-up comedian. Regan uses observational, sarcastic, and self-deprecating humor and his performances are relatively "clean" as he refrains from profanity and off-color humor. Regan's material typically covers everyday events, such as shipping a package with UPS and a visit to an optometrist. Regan makes frequent references to childhood, including little league baseball, grade school spelling bees, and science projects. His clean, off-cen ...